
Impurity standard manufacturer and Suppliers | Pharmaffiliates
Pharmaffiliates is the world's leading manufacturer /suppliers/exporter of impurity standards. We offer Certified Reference Standards of impurities, metabolites
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4693132001 | Sigma-Aldrich
Product Results Technical Documents Site Content Papers Available for Sale USA Globally Search term: "4693132001" Compare Products: Select up to 4 products. *Please select more than one item to compare 1
Online MessageSirolimus | C51H79NO13 - PubChem
Although the sirolimus-(FKBP-12) complex is inactive against calcineurin activity, the complex binds to and inhibits activation of a key regulatory kinase, mammalian Target of Rapamycin (mTOR). This is believed to suppress cytokine-driven T-cell
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Toronto Research Chemicals 20 Martin Ross Avenue North York, ON Canada, M3J 2K8 International: +1 (416) 665-9696 Fax:+1 (416) 665-4439 US & Canada: +1(800)727-9240 Email: [email protected]TRC partners with LGC Standards
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Limitations of immunoassays used for therapeutic drug monitoring of immunosuppressants - ScienceDirect
1/1/2016 · For therapeutic drug monitoring of immunosuppressants, several immunoassays are available commercially. These assays are listed in Table 2.1.In general, for analysis of cyclosporine, tacrolimus, sirolimus, and everolimus, pretreatment of whole
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CAS No : 140171-65-9| Product Name : Amlodipine Besilate - Impurity E| Chemical Name : Amlodipine Diethyl Ester | Pharmaffiliates
Buy highly pure Amlodipine Besilate - Impurity E, CAS No : 140171-65-9, Mol.Formula : C21H27ClN2O5, Mol.Weight : 422.9, from Pharmaffiliates. Login as registered user for prices, availability and discounts. Catalogue number: PA 01 50050 Chemical
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Dimethyl sulfoxide
Dimethyl sulfoxide (DMSO) is an organosulfur compound with the formula (CH3)2SO. This colorless liquid is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as
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LGC Standards
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MedChemExpress (MCE): Inhibitors, Agonists & Screening Libraies | Master of Small Molecules
MedChemExpress provides 15,000+ selective Inhibitors and Agonists with high purity and quality. Cited in 15,000+ publications and trusted by worldwide scientists. Cancer Cell. 2020 Nov 12. Cell Metab. 2020 Nov 6;S1550-4131(20)30545-3. Cell Res.
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2-methyl-2-propanol | Sigma-Aldrich
12 Product Results | Match Criteria: Product Name SynonymProduct Name, Property, Description Linear Formula: BrCH 2 CH(CH 3)CH 2 OH Molecular Weight: 153.02 CAS Number: 93381-28-3 325066 97% pricing SDS ()-(+)-3-Bromo-2-methyl-1-propanol
Online MessageTemsirolimus | C56H87NO16 - PubChem
Temsirolimus is an ester analog of rapamycin.Temsirolimus binds to and inhibits the mammalian target of rapamycin (mTOR), resulting in decreased expression of mRNAs necessary for cell cycle progression and arresting cells in the G1 phase of the
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An Efficient Method To Generate Gene Deletion Mutants of the Rapamycin-Producing Bacterium Streptomyces iranensis HM 35 | Applied and ...
Streptomyces iranensis HM 35 is an alternative rapamycin producer to Streptomyces rapamycinicus. Targeted genetic modification of rapamycin-producing actinomycetes is a powerful tool for the directed production of rapamycin derivatives, and it
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Improvement of FK506 Production in Streptomyces tsukubaensis by Genetic Enhancement of the Supply of Unusual Polyketide Extender Units via ...
FK506 is a potent immunosuppressant that has a wide range of clinical applications. Its 23-member macrocyclic scaffold, mainly with a polyketide origin, features two methoxy groups at C-13 and C-15 and one allyl side chain at C-21, due to the
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Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A ...
We report here that des-methyl, des-amino pateamine A (DMDA-PatA), a structurally simplified analogue of the marine natural product pateamine A, has potent antiproliferative activity against a wide variety of human cancer cell lines while
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mTOR Inhibitor | Buy mTOR Inhibitors at Adooq
LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and DNA-PK, extracted from patent WO/2012097039A1, compound example 1, has an IC50 of 64.9 nM, 42.1 nM, 10.6 nM, 19.1 nM for Akt1(pT308), Akt1 (pS473), P70S6(pT389
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Product Page - TLC
Compound Name: Everolimus Synonyms: 42-O-(2-hydroxyethyl)-Rapamycin CAS#: 159351-69-6 Alternate CAS#: Molecular Formula: C 53 H 83 NO 14 Molecular Weight: 958.24 Download SDS Related Product E-102 Everolimus-d4 CAS No. 1338452-54-2...
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BOC Sciences | Address: 45-16 Ramsey Road, Shirley, New York 11967, USA https://www.bocsci | Send Inquiry | Phone: +1-(631)-619-7922 | jessica.byee BOC Sciences provides a wide range of Customer Services, Bulk & Specialty Compounds to the
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Worldwide distributors | Where to buy TRC products - Toronto Research Chemicals | Products for innovative research
Pharmaffiliates Analytics & Synthetics 1-A Parichay Park Diwalipura Road Vadodara, Gujarat India, 390007 # 308, 3rd floor,12, Jalan Temenggong Taman Desawira 42500 Telok P. Garang Selangor Malaysia No 3, Level 1&2, Jalan USJ 1/31,
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Generation of Multiple Bioactive Macrolides by Hybrid Modular Polyketide Synthases in Streptomyces venezuelae - ScienceDirect
1/2/2002 · The plasmid-based replacement of the multifunctional protein subunits of the pikromycin PKS in S. venezuelae by the corresponding subunits from heterologous modular PKSs resulted in recombinant strains that produce both 12- and 14-membered ring
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